Jan 10, 2027SF at ARIState Farm StadiumUPCOMINGJan 3, 2027PHI at SFLevi's StadiumUPCOMINGDec 27, 2026SF at KCArrowhead StadiumUPCOMINGDec 17, 2026SF at LACSoFi StadiumUPCOMINGDec 13, 2026LAR at SFLevi's StadiumUPCOMINGDec 6, 2026SF at NYGMetLife StadiumUPCOMINGNov 29, 2026SEA at SFLevi's StadiumUPCOMINGNov 22, 2026MIN at SFEstadio BanorteUPCOMINGNov 15, 2026SF at DALAT&T StadiumUPCOMINGNov 8, 2026LV at SFLevi's StadiumUPCOMINGOct 25, 2026SF at ATLMercedes-Benz StadiumUPCOMINGOct 19, 2026WSH at SFLevi's StadiumUPCOMINGOct 11, 2026SF at SEALumen FieldUPCOMINGOct 4, 2026DEN at SFLevi's StadiumUPCOMINGSep 27, 2026
Nick Bosa · QuestionableCoach Kyle Shanahan said Tuesday that Bosa has missed recent practices due to soreness/tendinitis in his right knee, and the pass rusher is considered week-to-week, Noah Furtado of the San Francisco Chronicle reports.
George Kittle · PUP-PKittle (Achilles) was seen running routes, catching passes and doing conditioning work prior to Monday's practice, Nick Wagoner of ESPN.com reports.
Christian Kirk · QuestionableKirk (calf) is not suited up for Thursday's preseason opener against the Titans, Nick Wagoner of ESPN.com reports.
Mike Evans · QuestionableEvans (quadriceps) is not dressed in uniform for Thursday night's preseason opener against the Titans, Nick Wagoner of ESPN.com reports.
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